J.P. Macura scored 18 points and No. 11 Xavier took advantage of 38 personal fouls by Buffalo, pulling away for an 86-53 victory on Monday night.
The Musketeers (2-0) quickly opened a double-digit lead and got the balance back in their offense after relying on career highs for points by Trevon Bluiett and Edmond Sumner in their opening 84-81 win over Lehigh. Bluiett and Sumner had 13 points apiece on Monday.
Buffalo (1-1) couldn't keep up with Xavier's quickness and quickly got into foul trouble. The Bulls trailed 42-22 late in the first half and had more fouls (23) than points.
Two Bulls fouled out with 8 minutes left in the game, and Xavier went 28 of 38 at the line. Macura made all of his 10 free throws.
Nick Perkins led the Bulls with 15 points. They shot only 31 percent from the field.