Orlando, FL (ABCNews.com) -- At least two people were killed and five injured in a shooting at an office building in downtown Orlando, Fla., according to authorities.

About 20 people were led out of the building, distraught and crying, according to reports by ABC's Eyewitness News WFTV.

Police said they are going floor-by-floor looking for more victims, but wouldn't confirm whether the shooter was still at-large.

Four victims were transported to the local hospital and described as "trauma red" patients, according to Orlando police and fire departments.

The shootings happened at the Legion Place Gateway Center. Due to the incident, I-4 at SR-50 is closed and Edgewater High School is on lock down.

One witness said he saw someone screaming at him to get out of the building immediately.

There were approximately 50 paramedics responding to the incident.

No other details were available at the time.

Stay with Eyewitness News and WKBW.com for latest on this breaking story.